2-TrifluoroMethylpyridine-3-acetic acid
(2-Trifluoromethyl-pyridin-3-yl)-acetic acid
CAS: 1000568-14-8
Molecular Formula: C8H6F3NO2
2-TrifluoroMethylpyridine-3-acetic acid - Names and Identifiers
2-TrifluoroMethylpyridine-3-acetic acid - Physico-chemical Properties
| Molecular Formula | C8H6F3NO2 |
| Molar Mass | 205.13 |
| Density | 1.428±0.06 g/cm3(Predicted) |
| Boling Point | 268.4±35.0 °C(Predicted) |
| pKa | 3.83±0.10(Predicted) |
2-TrifluoroMethylpyridine-3-acetic acid - Introduction
(2-Trifluoromethyl-pyridin-3-yl)-acetic acid, also known as TFP acid or TFAA, is an organic compound. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: colorless liquid
Use:
- TFP acid is commonly used as an acylating reagent in organic synthesis, which can convert anhydrides into corresponding esters.
-It can also be used to adjust the acid-base conditions of chemical reactions and catalyze certain reactions.
- TFP acids are widely used in the preparation of fatty acids, peptides, proteins and other compounds.
-In liquid chromatography analysis, TFP acid is often used as an additive in the mobile phase.
Preparation Method:
(2-Trifluoromethyl-pyridin-3-yl)-acetic acid can be prepared by reacting 2-(trifluoromethyl) pyridin -3-amine with acetic anhydride under appropriate reaction conditions.
Safety Information:
- TFP acid is irritating and corrosive. Pay attention to protective measures when contacting skin and eyes.
-Use should be operated in a well-ventilated place to avoid inhalation of gas and steam.
-Avoid contact with combustibles, away from open flames and heat sources.
-Observe appropriate safety procedures and regulations during storage and handling.
Last Update：2024-04-09 19:55:45
